The appearance of an L1-like molecule in the chick primary visual pathway.
نویسندگان
چکیده
A monoclonal antibody, 8D9, has been obtained that binds to axons in the chick nervous system. Biochemical and immunological experiments indicate that the 8D9 antigen is related to the mouse L1 cell-adhesion molecule. The results of immunohistochemical experiments using monoclonal antibody 8D9 to study the development of the chick visual system are consistent with the 8D9 antigen functioning in axon fasciculation.
منابع مشابه
L1 Transfer in L2 Acquisition of the There-Insertion Construction by Mandarin EFL Learners
This study examined the role of the native language (L1) transfer in a non-native language (L2) acquisition of the there-insertion construction at the syntax-semantics interface. Specifically, the study investigated if Mandarin EFL learners would make overgeneralization errors in the situation where an L1 argument structure constitutes a superset of its L2 counterpart. Verbs of existence and ap...
متن کاملThe monoclonal antibody E587 recognizes growing (new and regenerating) retinal axons in the goldfish retinotectal pathway.
E587 is a new monoclonal antibody against a 200 kDa cell-surface glycoprotein in the fish retinotectal pathway. The E587 antigen probably belongs to the class of cell adhesion molecules, and more specifically, to the family of L1-like molecules. The immunopurified protein is recognized by the antibody against the HNK1/L2 sugar epitope (associated with most cell adhesion molecules) and by a poly...
متن کاملThe effect of bone marrow-derived mesenchymal stem cells to induce PD-L1 molecule on splenic lymphocytes
Background: Mesenchymal stem cells are non-hematopoietic stromal cells that are used in the treatment of many chronic and autoimmune diseases by modulating the immune system. Due to the limitations of using autologous mesenchymal stem cells, the use of allogeneic stem cells is a promising therapeutic approach in the treatment of immunological disorders. This study aimed to investigate the abili...
متن کاملHistomorphometric study of the spinal cord segments in the chick and adult male ostrich (Struthio camelus)
In this study, the vertical, transverse and oblique diameters of the spinal cord segments (C1, C6, C12, C18, T1, T4, L1, L4, L6 and L8) and the ratio of gray matter to white matter in chick (l month) and adult (18 months) male ostriches, each group consisted of 3 animals, were measured with standard micrometric method using 6 μm thick sections by light microscope. With advancement of age, the r...
متن کاملTopologically restricted appearance in the developing chick retinotectal system of Bravo, a neural surface protein: experimental modulation by environmental cues
A novel neural surface protein, Bravo, shows a pattern of topological restriction in the embryonic chick retinotectal system. Bravo is present on the developing optic fibers in the retina; however, retinal axons in the tectum do not display Bravo. The appearance of Bravo in vitro is modulated by environmental cues. Axons growing out from retinal explants on retinal basal lamina, their natural s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of neuroscience : the official journal of the Society for Neuroscience
دوره 6 10 شماره
صفحات -
تاریخ انتشار 1986